Tau is a microtubule-associated protein that helps to stabilize the structure of neurons, specifically by supporting microtubules, cylindrical structures that contribute to cell motility, intracellular transport and the maintenance of a cell's shape over time. While...
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder associated with a progressive decline in memory and mental abilities, which can significantly hinder people's ability to complete daily tasks. Past studies found that patients diagnosed with AD, as...
Astrocytes are star-shaped glial cells in the central nervous system that support neuronal function, maintain the blood-brain barrier, and contribute to brain repair and homeostasis. The evolution of these cells throughout the progression of Alzheimer's disease (AD)...
Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD) are highly debilitating medical conditions arising from a combination of genetic and environmental factors. Studies exploring the neural underpinnings of these diseases and how...
Microglia are primary immune cells that safeguard the mammalian brain, partly by devouring or 'phagocytosing' pathogens and toxic debris. Recent genetic studies have consistently highlighted the role of microglia in the development of Alzheimer's disease (AD) and...
Researchers at Emory University School of Medicine have recently carried out a large-scale analysis of the brains of patients with Alzheimer's disease (AD). Their findings, published in Nature Neuroscience, unveiled a series of disease-related changes in protein...