An ischemic stroke is a type of stroke that occurs when a blood clot in an artery, also known as thrombus, or the progressive narrowing of arteries, blocks the blood and oxygen flowing to the brain. This process can cause both temporary and permanent brain damage, for...
Immunology
A neural mechanism that could underlie fasting-mediated immune regulation
Fasting, the voluntary abstention from eating and sometimes drinking for a set time, has become increasingly widespread, as some studies have found that it could boost the immune system and help prevent the development of some diseases. There are now several...
An immune molecule that regulates aging and a living organism’s lifespan
Aging is a natural process that affects all living organisms, prompting gradual changes in their behavior and abilities. Past studies have highlighted several physiological factors that can contribute to aging, including the body's immune responses, an imbalance...
Study shows that the translation of protein by microglia supports efficient phagocytosis
Recent studies have found that some cells of the brain, including neurons, astrocytes, and oligodendrocytes, can transport pieces of the genetic code (RNA) from the nucleus out to their distal processes which may be several microns away, and then locally translate...
A TREM2 activating antibody with a transport vehicle that could boost the metabolism and function of brain microglia
The protein TREM2, which in humans is encoded by the TREM2 gene, is known to play a crucial role in the growth and development of different types of immune cells, including microglia. Microglia are specialized immune cells in the central nervous system that help to...
Study shows that adaptive immune responses can cause cellular loss in the aging brain
Past neuroscience studies have consistently demonstrated that the aging of the mammalian nervous system is liked with a decline in the volume and functioning of white matter, nerve fibers found in deep brain tissues. Although this is now a well-established finding,...
Study unveils pro-inflammatory interactions in drug-resistant epilepsy
Epilepsy is a common condition that causes those affected to experience frequent seizures, which are bursts of electrical activity in the brain that temporarily impair its functioning. These seizures can present differently and can be associated with uncontrollable...
Study explores the effects of immune responses on the aging brain
As human beings age, the functioning of organs gradually deteriorates. While countless past studies have investigated the effects of aging on the human body, brain and on cognition, the neural mechanisms and environmental factors that can accelerate or slow down these...